PDE9A 抗体
Quick Overview for PDE9A 抗体 (ABIN7117437)
抗原
See all PDE9A 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- PDE9A antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- phosphodiesterase 9A
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亚型
- IgG
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anti-phosphodiesterase 9A (PDE9A) (AA 1-533) antibody
PDE9A 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 9A (PDE9A) (N-Term) antibodyPDE9A 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 9A (PDE9A) (AA 426-533) antibodyPDE9A 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 9A (PDE9A) (AA 434-533) antibodyPDE9A 适用: 人 ELISA, WB, IHC (p) 宿主: 小鼠 Monoclonal 1E1 unconjugated
anti-phosphodiesterase 9A (PDE9A) (N-Term) antibodyPDE9A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 9A (PDE9A) (AA 1-533) antibodyPDE9A 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-phosphodiesterase 9A (PDE9A) (AA 136-185) antibodyPDE9A 适用: 人, 犬 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC: 1:100-1:200, IF: 1:50-1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- PDE9A (phosphodiesterase 9A (PDE9A))
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别名
- PDE9A
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背景
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Synonyms: High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A|PDE9A
Background: Specifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity and selectivity for cGMP(PubMed:9624146, PubMed:18757755, PubMed:21483814). Specifically regulates natriuretic-peptide-dependent cGMP signaling in heart, acting as a regulator of cardiac hypertrophy in myocytes and muscle. Does not regulate nitric oxide-dependent cGMP in heart(PubMed:25799991). Additional experiments are required to confirm whether its ability to hydrolyze natriuretic-peptide-dependent cGMP is specific to heart or is a general feature of the protein(Probable). In brain, involved in cognitive function, such as learning and long-term memory(By similarity).
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基因ID
- 5152
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UniProt
- O76083
抗原
-
