PDE9A 抗体
Our Local Distributor
北京 101111
Quick Overview for PDE9A 抗体 (ABIN7117437)
抗原
See all PDE9A 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- PDE9A antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- phosphodiesterase 9A
-
亚型
- IgG
-
-
anti-phosphodiesterase 9A (PDE9A) (AA 1-533) antibody
PDE9A 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 9A (PDE9A) (N-Term) antibodyPDE9A 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 9A (PDE9A) (AA 426-533) antibodyPDE9A 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 9A (PDE9A) (AA 434-533) antibodyPDE9A 适用: 人 ELISA, WB, IHC (p) 宿主: 小鼠 Monoclonal 1E1 unconjugated
anti-phosphodiesterase 9A (PDE9A) (N-Term) antibodyPDE9A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 9A (PDE9A) (AA 1-533) antibodyPDE9A 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-phosphodiesterase 9A (PDE9A) (AA 136-185) antibodyPDE9A 适用: 人, 犬 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- IHC: 1:100-1:200, IF: 1:50-1:500
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- PDE9A (phosphodiesterase 9A (PDE9A))
-
别名
- PDE9A
-
背景
-
Synonyms: High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A|PDE9A
Background: Specifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity and selectivity for cGMP(PubMed:9624146, PubMed:18757755, PubMed:21483814). Specifically regulates natriuretic-peptide-dependent cGMP signaling in heart, acting as a regulator of cardiac hypertrophy in myocytes and muscle. Does not regulate nitric oxide-dependent cGMP in heart(PubMed:25799991). Additional experiments are required to confirm whether its ability to hydrolyze natriuretic-peptide-dependent cGMP is specific to heart or is a general feature of the protein(Probable). In brain, involved in cognitive function, such as learning and long-term memory(By similarity).
-
基因ID
- 5152
-
UniProt
- O76083
抗原
-
