PPIL2 抗体
Quick Overview for PPIL2 抗体 (ABIN7117300)
抗原
See all PPIL2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- PPIL2 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- peptidylprolyl isomerase(cyclophilin)-like 2
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- PPIL2 (Peptidylprolyl Isomerase (Cyclophilin)-Like 2 (PPIL2))
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别名
- PPIL2
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背景
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Synonyms: RING-type E3 ubiquitin-protein ligase PPIL2|CYC4|Cyclophilin-60 (Cyclophilin-like protein Cyp-60, Cyp60, hCyP-60)|Probable inactive peptidyl-prolyl cis-trans isomerase-like 2 (PPIase)|Rotamase PPIL2|PPIL2
Background: May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides thereby assisting the folding of proteins(By similarity). May also function as a chaperone, playing a role in transport to the cell membrane of BSG for instance(PubMed:15946952). May also have a protein ubiquitin ligase activity acting as an E3 ubiquitin protein ligase or as an ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on substrates. By mediating 'Lys-48'-linked polyubiquitination of proteins could target them for proteasomal degradation(PubMed:11435423).
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分子量
- 59 kDa
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基因ID
- 23759
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UniProt
- Q13356
抗原
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