PELI2 抗体
Quick Overview for PELI2 抗体 (ABIN7117276)
抗原
See all PELI2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- PELI2 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- pellino homolog 2(Drosophila)
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亚型
- IgG
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anti-Pellino Homolog 2 (Drosophila) (PELI2) (AA 1-420) antibody
PELI2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Pellino Homolog 2 (Drosophila) (PELI2) (N-Term) antibodyPELI2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Pig, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Pellino Homolog 2 (Drosophila) (PELI2) (AA 22-51), (N-Term) antibodyPELI2 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- PELI2 (Pellino Homolog 2 (Drosophila) (PELI2))
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别名
- PELI2
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背景
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Synonyms: E3 ubiquitin-protein ligase pellino homolog 2 (Pellino-2)|RING-type E3 ubiquitin transferase pellino homolog 2|PELI2
Background: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates IL1B-induced IRAK1 'Lys-63'-linked polyubiquitination and possibly 'Lys-48'-linked ubiquitination. May be important for LPS-and IL1B-induced MAP3K7-dependent, but not MAP3K3-dependent, NF-kappa-B activation. Can activate the MAP(mitogen activated protein) kinase pathway leading to activation of ELK1.
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分子量
- 45-50 kDa
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基因ID
- 57161
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UniProt
- Q9HAT8
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途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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