PDZK1 抗体
Quick Overview for PDZK1 抗体 (ABIN7117270)
抗原
See all PDZK1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- PDZK1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- PDZ domain containing 1
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亚型
- IgG
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应用备注
- WB: 1:500 - 1:2000, IHC: 1:20 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- PDZK1 (PDZ Domain Containing 1 (PDZK1))
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别名
- PDZK1
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背景
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Synonyms: Na(+)/H(+) exchange regulatory cofactor NHE-RF3 (NHERF-3)|CFTR-associated protein of 70 kDa|Na(+)/H(+) exchanger regulatory factor 3|Na/Pi cotransporter C-terminal-associated protein 1 (NaPi-Cap1)|PDZ domain-containing protein 1|Sodium-hydrogen exchanger regulatory factor 3|PDZK1|CAP70|NHERF3|PDZD1
Background: This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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分子量
- 67 kDa
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基因ID
- 5174
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UniProt
- Q5T2W1
抗原
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