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PARD3 抗体

PARD3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, FACS, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7117224
发货至: 中国
  • 抗原 See all PARD3 抗体
    PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))
    适用
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    人, 小鼠, 大鼠
    宿主
    • 53
    • 3
    克隆类型
    • 55
    • 1
    多克隆
    标记
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    This PARD3 antibody is un-conjugated
    应用范围
    • 42
    • 23
    • 13
    • 13
    • 11
    • 9
    • 6
    • 3
    • 3
    • 2
    • 2
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunoprecipitation (IP)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    Partitioning defective 3 homolog
    亚型
    IgG
    Top Product
    Discover our top product PARD3 Primary Antibody
  • 应用备注
    WB: 1:500-1:1000, IP: 1:200-1:1000, IHC: 1:50-1:200, IF: 1:50-1:500
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))
    别名
    PARD3 (PARD3 产品)
    背景
    Synonyms:ASIP, Baz, Bazooka, CTCL tumor antigen se2 5, FLJ21015, PAR 3, PAR3, PAR3 alpha, PAR3A, PAR3alpha, PARD 3, PARD3, PARD3A, SE2 5L16, SE2 5LT1, SE2 5T2 Background:Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Targets the phosphatase PTEN to cell junctions. Involved in Schwann cell peripheral myelination(By similarity). Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons.PARD3 has three splice isoforms at 100 kDa, 150 kDa, and 180 kDa. This polyclonal antibody raised against C-terminal 281 amino acids of human PARD3 recognizes these three isoforms.
    分子量
    100 kDa, 150 kDa, and 180 kDa
    基因ID
    56288
    UniProt
    Q8TEW0
    途径
    Cell-Cell Junction Organization
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