TENT4B (AA 400-465) 抗体
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北京 101111
Quick Overview for TENT4B (AA 400-465) 抗体 (ABIN7117222)
抗原
适用
宿主
克隆类型
应用范围
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抗原表位
- AA 400-465
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原理
- TENT4B antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 400-465aa
Immunogen: PAP associated domain containing 5
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亚型
- IgG
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应用备注
- WB: 1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- TENT4B
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背景
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Synonyms: Terminal nucleotidyltransferase 4B|Non-canonical poly(A) RNA polymerase PAPD5|PAP-associated domain-containing protein 5|Terminal guanylyltransferase|Terminal uridylyltransferase 3 (TUTase 3)|Topoisomerase-related function protein 4-2 (TRF4-2)|TENT4B|GLD4|PAPD5|TRF4-2|TUT3
Background: Catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Doesn't need a cofactor for polyadenylation activity(in vitro). Plays a role in replication-dependent histone mRNA degradation, probably through terminal uridylation of mature histone mRNAs. May play a role in sister chromatid cohesion.
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分子量
- 50 kDa, 80 kDa
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基因ID
- 64282
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UniProt
- Q8NDF8
抗原
-
