PAK1IP1 抗体
Quick Overview for PAK1IP1 抗体 (ABIN7117207)
抗原
See all PAK1IP1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- PAK1IP1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- PAK1 interacting protein 1
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- PAK1IP1 (PAK1 Interacting Protein 1 (PAK1IP1))
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别名
- PAK1IP1
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背景
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Synonyms: p21-activated protein kinase-interacting protein 1|PAK/PLC-interacting protein 1 (hPIP1)|PAK1-interacting protein 1|WD repeat-containing protein 84|PAK1IP1|PIP1|WDR84
Background: Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which have been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42.
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分子量
- 44 kDa
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基因ID
- 55003
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UniProt
- Q9NWT1
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途径
- Telomere Maintenance
抗原
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