NFX1 抗体
Quick Overview for NFX1 抗体 (ABIN7117021)
抗原
See all NFX1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- NFX1 antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- nuclear transcription factor, X-box binding 1
-
亚型
- IgG
-
-
-
-
应用备注
- WB: 1:500-1:2000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- NFX1 (Nuclear Transcription Factor, X-Box Binding 1 (NFX1))
-
别名
- NFX1
-
背景
-
Synonyms: Transcriptional repressor NF-X1|Nuclear transcription factor, X box-binding protein 1|NFX1|NFX2
Background: Binds to the X-box motif of MHC class II genes and represses their expression. May play an important role in regulating the duration of an inflammatory response by limiting the period in which MHC class II molecules are induced by interferon-gamma. Isoform 3 binds to the X-box motif of TERT promoter and represses its expression. Together with PABPC1 or PABPC4, isoform 1 acts as a coactivator for TERT expression. Mediates E2-dependent ubiquitination.
-
分子量
- 124 kDa
-
基因ID
- 4799
-
UniProt
- Q12986
抗原
-