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NFIL3 抗体

This anti-NFIL3 antibody is a 兔 多克隆 antibody detecting NFIL3 in WB, ELISA 和 IP. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7116970
发货至: 中国

Quick Overview for NFIL3 抗体 (ABIN7116970)

抗原

See all NFIL3 抗体
NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))

适用

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人, 小鼠, 大鼠

宿主

  • 36
  • 1
  • 1

克隆类型

  • 38
多克隆

标记

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  • 2
  • 1
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This NFIL3 antibody is un-conjugated

应用范围

  • 31
  • 16
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Western Blotting (WB), ELISA, Immunoprecipitation (IP)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    nuclear factor, interleukin 3 regulated

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IP: 1:200-1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))

    别名

    NFIL3

    背景

    Synonyms:E4BP4, IL3BP1 Background:Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor(ATF) sites. Represses promoter activity in osteoblasts(By similarity). Represses transcriptional activity of PER1(By similarity). Represses transcriptional activity of PER2 via the B-site on the promoter(By similarity). Activates transcription from the interleukin-3 promoter in T-cells. Competes for the same consensus-binding site with PAR DNA-binding factors(DBP, HLF and TEF)(By similarity). Component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock(By similarity). Protects pro-B cells from programmed cell death(By similarity).

    分子量

    55-60 kDa

    基因ID

    4783

    UniProt

    Q16649
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