NFIL3 抗体
Quick Overview for NFIL3 抗体 (ABIN7116970)
抗原
See all NFIL3 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- NFIL3 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- nuclear factor, interleukin 3 regulated
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))
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别名
- NFIL3
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背景
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Synonyms: Nuclear factor interleukin-3-regulated protein|E4 promoter-binding protein 4|Interleukin-3 promoter transcriptional activator|Interleukin-3-binding protein 1|Transcriptional activator NF-IL3A|NFIL3|E4BP4|IL3BP1
Background: Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor(ATF) sites. Represses promoter activity in osteoblasts(By similarity). Represses transcriptional activity of PER1(By similarity). Represses transcriptional activity of PER2 via the B-site on the promoter(By similarity). Activates transcription from the interleukin-3 promoter in T-cells. Competes for the same consensus-binding site with PAR DNA-binding factors(DBP, HLF and TEF)(By similarity). Component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock(By similarity). Protects pro-B cells from programmed cell death(By similarity).
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分子量
- 55-60 kDa
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基因ID
- 4783
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UniProt
- Q16649
抗原
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