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Nth Endonuclease III-Like 1 (NTHL1) 抗体

This anti- antibody is a 兔 多克隆 antibody detecting in WB, ELISA 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7116939
发货至: 中国

Quick Overview for Nth Endonuclease III-Like 1 (NTHL1) 抗体 (ABIN7116939)

抗原

See all Nth Endonuclease III-Like 1 (NTHL1) 抗体
Nth Endonuclease III-Like 1 (NTHL1)

适用

  • 34
  • 5
  • 5
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 38
  • 2

克隆类型

  • 34
  • 6
多克隆

标记

  • 25
  • 7
  • 4
  • 2
  • 1
  • 1
非结合性

应用范围

  • 30
  • 25
  • 9
  • 6
  • 5
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    nth endonuclease III-like 1(E. coli)

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IHC: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    Nth Endonuclease III-Like 1 (NTHL1)

    别名

    NTHL1

    背景

    Synonyms:NTH1, OCTS3 Background:Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic(AP) lyase function that catalyzes the first step in base excision repair(BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. Has also 8-oxo-7,8-dihydroguanine(8-oxoG) DNA glycosylase activity. Acts preferentially on DNA damage opposite guanine residues in DNA. Is able to process lesions in nucleosomes without requiring or inducing nucleosome disruption.

    分子量

    34 kDa

    基因ID

    4913

    UniProt

    P78549
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