Nth Endonuclease III-Like 1 (NTHL1) 抗体
Quick Overview for Nth Endonuclease III-Like 1 (NTHL1) 抗体 (ABIN7116939)
抗原
See all Nth Endonuclease III-Like 1 (NTHL1) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- NTHL1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- nth endonuclease III-like 1(E. coli)
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亚型
- IgG
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anti-Nth Endonuclease III-Like 1 (NTHL1) (AA 31-312) antibody
NTHL1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nth Endonuclease III-Like 1 (NTHL1) antibodyNTHL1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nth Endonuclease III-Like 1 (NTHL1) (AA 1-280) antibodyNTHL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Nth Endonuclease III-Like 1 (NTHL1) antibodyNTHL1 适用: 人 WB, DB 宿主: 小鼠 Monoclonal 2660C1a unconjugated
anti-Nth Endonuclease III-Like 1 (NTHL1) (Center) antibodyNTHL1 适用: 人 IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nth Endonuclease III-Like 1 (NTHL1) (AA 88-117) antibodyNTHL1 适用: 人 WB 宿主: 兔 Polyclonal RB17473 unconjugated
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- Nth Endonuclease III-Like 1 (NTHL1)
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别名
- NTHL1
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背景
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Synonyms: Endonuclease III-like protein 1 (hNTH1)|Bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase (DNA glycosylase/AP lyase)|NTHL1|NTH1|OCTS3
Background: Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic(AP) lyase function that catalyzes the first step in base excision repair(BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. Has also 8-oxo-7,8-dihydroguanine(8-oxoG) DNA glycosylase activity. Acts preferentially on DNA damage opposite guanine residues in DNA. Is able to process lesions in nucleosomes without requiring or inducing nucleosome disruption.
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分子量
- 34 kDa
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基因ID
- 4913
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UniProt
- P78549
抗原
-
