NSUN2 抗体
Quick Overview for NSUN2 抗体 (ABIN7116925)
抗原
See all NSUN2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- NSUN2 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- NOL1/NOP2/Sun domain family, member 2
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))
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别名
- NSUN2
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背景
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Synonyms: RNA cytosine C(5)-methyltransferase NSUN2|Myc-induced SUN domain-containing protein (Misu)|NOL1/NOP2/Sun domain family member 2|Substrate of AIM1/Aurora kinase B|mRNA cytosine C(5)-methyltransferase|tRNA cytosine C(5)-methyltransferase|tRNA methyltransferase 4 homolog (hTrm4)|NSUN2|SAKI|TRM4
Background: RNA methyltransferase that methylates tRNAs, and possibly RNA polymerase III transcripts. Methylates cytosine to 5-methylcytosine(m5C) at positions 34 and 48 of intron-containing tRNA(Leu)(CAA) precursors, and at positions 48, 49 and 50 of tRNA(Gly)(GCC) precursors. May act downstream of Myc to regulate epidermal cell growth and proliferation. Required for proper spindle assembly and chromosome segregation, independently of its methyltransferase activity.
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分子量
- 90-100 kDa
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基因ID
- 54888
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UniProt
- Q08J23
抗原
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