NMNAT3 抗体
Quick Overview for NMNAT3 抗体 (ABIN7116866)
抗原
See all NMNAT3 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- NMNAT3 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- nicotinamide nucleotide adenylyltransferase 3
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- NMNAT3 (Nicotinamide Nucleotide Adenylyltransferase 3 (NMNAT3))
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别名
- NMNAT3
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背景
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Synonyms: Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 (NMN/NaMN adenylyltransferase 3)|Nicotinamide-nucleotide adenylyltransferase 3 (NMN adenylyltransferase 3)|Nicotinate-nucleotide adenylyltransferase 3 (NaMN adenylyltransferase 3)|Pyridine nucleotide adenylyltransferase 3 (PNAT-3)|NMNAT3
Background: Catalyzes the formation of NAD(+) from nicotinamide mononucleotide(NMN) and ATP. Can also use the deamidated form, nicotinic acid mononucleotide(NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate(TrMP) as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, can use NAD(+), NADH, NaAD, nicotinic acid adenine dinucleotide phosphate(NHD), nicotinamide guanine dinucleotide(NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NaADP(+). Protects against axonal degeneration following injury.
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分子量
- 24-28 kDa
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基因ID
- 349565
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UniProt
- Q96T66
抗原
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