NHP2 抗体
Quick Overview for NHP2 抗体 (ABIN7116860)
抗原
See all NHP2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- NHP2 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- NHP2 ribonucleoprotein homolog
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亚型
- IgG
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应用备注
- WB: 1:500-1:1000, IP: 1:500-1:1000, IHC: 1:20-1:200, IF: 1:10-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- NHP2 (NHP2 Ribonucleoprotein (NHP2))
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别名
- NHP2
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背景
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Synonyms: H/ACA ribonucleoprotein complex subunit 2|Nucleolar protein family A member 2|snoRNP protein NHP2|NHP2|NOLA2
Background: Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein(H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase(TERT) holoenzyme.
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分子量
- 17-20 kDa
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基因ID
- 55651
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UniProt
- Q9NX24
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途径
- Telomere Maintenance
抗原
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