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NGEF 抗体

NGEF 适用: 人, 小鼠 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7116830
发货至: 中国
  • 抗原 See all NGEF 抗体
    NGEF (Neuronal Guanine Nucleotide Exchange Factor (NGEF))
    适用
    • 37
    • 36
    • 29
    • 4
    • 4
    • 4
    • 4
    人, 小鼠
    宿主
    • 43
    • 1
    克隆类型
    • 43
    • 1
    多克隆
    标记
    • 8
    • 3
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    • 2
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    • 2
    • 2
    • 2
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    • 2
    • 2
    • 1
    • 1
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    This NGEF antibody is un-conjugated
    应用范围
    • 40
    • 26
    • 26
    • 11
    • 6
    • 6
    • 2
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    neuronal guanine nucleotide exchange factor
    亚型
    IgG
    Top Product
    Discover our top product NGEF Primary Antibody
  • 应用备注
    WB: 1:500-1:1000, IP: 1:500-1:1000, IHC: 1:50-1:500
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    NGEF (Neuronal Guanine Nucleotide Exchange Factor (NGEF))
    别名
    NGEF (NGEF 产品)
    别名
    Ephexin-1 antibody, ARHGEF27 antibody, EPHEXIN antibody, Tims2 antibody, ephexin antibody, Besh3 antibody, ephexin-1 antibody, neuronal guanine nucleotide exchange factor antibody, NGEF antibody, Ngef antibody
    背景
    Synonyms: Background:Acts as a guanine nucleotide exchange factor(GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1-and CDC42-stimulated growth cone extension(By similarity).
    分子量
    75 kDa
    基因ID
    25791
    UniProt
    Q8N5V2
    途径
    Neurotrophin Signaling Pathway
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