NrCAM 抗体
Quick Overview for NrCAM 抗体 (ABIN7116828)
抗原
See all NrCAM (NRCAM) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- NRCAM antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- neuronal cell adhesion molecule
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- NrCAM (NRCAM) (Neuronal Cell Adhesion Molecule (NRCAM))
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别名
- NRCAM
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背景
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Synonyms: Neuronal cell adhesion molecule (Nr-CAM)|Neuronal surface protein Bravo (hBravo)|NgCAM-related cell adhesion molecule (Ng-CAM-related)|NRCAM|KIAA0343
Background: Cell adhesion protein that is required for normal responses to cell-cell contacts in brain and in the peripheral nervous system. Plays a role in neurite outgrowth in response to contactin binding. Plays a role in mediating cell-cell contacts between Schwann cells and axons. Plays a role in the formation and maintenance of the nodes of Ranvier on myelinated axons. Nodes of Ranvier contain clustered sodium channels that are crucial for the saltatory propagation of action potentials along myelinated axons. During development, nodes of Ranvier are formed by the fusion of two heminodes. Required for normal clustering of sodium channels at heminodes, not required for the formation of mature nodes with normal sodium channel clusters. Required, together with GLDN, for maintaining NFASC and sodium channel clusters at mature nodes of Ranvier.
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分子量
- 130-136 kDa
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基因ID
- 4897
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UniProt
- Q92823
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途径
- Regulation of Cell Size
抗原
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