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NCK1 抗体

This anti-NCK1 antibody is a 兔 多克隆 antibody detecting NCK1 in WB, IHC, ELISA, IF, FACS 和 IP. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7116754
发货至: 中国

Quick Overview for NCK1 抗体 (ABIN7116754)

抗原

See all NCK1 抗体
NCK1 (NCK Adaptor Protein 1 (NCK1))

适用

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人, 小鼠, 大鼠

宿主

  • 58
  • 7
  • 1

克隆类型

  • 50
  • 16
多克隆

标记

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This NCK1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunoprecipitation (IP)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    NCK adaptor protein 1

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    NCK1 (NCK Adaptor Protein 1 (NCK1))

    别名

    NCK1

    背景

    Synonyms:NCK Background:Adapter protein which associates with tyrosine-phosphorylated growth factor receptors, such as KDR and PDGFRB, or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in the DNA damage response, not in the detection of the damage by ATM/ATR, but for efficient activation of downstream effectors, such as that of CHEK2. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling. Modulates the activation of EIF2AK2/PKR by dsRNA. May play a role in cell adhesion and migration through interaction with ephrin receptors.

    分子量

    43kd

    基因ID

    4690

    UniProt

    P16333

    途径

    TCR Signaling, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
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