NCK1 抗体
Quick Overview for NCK1 抗体 (ABIN7116754)
抗原
See all NCK1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- NCK1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- NCK adaptor protein 1
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亚型
- IgG
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anti-NCK Adaptor Protein 1 (NCK1) antibody
NCK1 适用: 人, 猴 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 5B7 unconjugated
anti-NCK Adaptor Protein 1 (NCK1) (AA 185-294) antibodyNCK1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A1 unconjugated
anti-NCK Adaptor Protein 1 (NCK1) antibodyNCK1 适用: 人, 猴 WB, FACS, IHC (p), EIA 宿主: 小鼠 Monoclonal 5B7 unconjugated
anti-NCK Adaptor Protein 1 (NCK1) (AA 58-377) antibodyNCK1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-NCK Adaptor Protein 1 (NCK1) antibodyNCK1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-NCK Adaptor Protein 1 (NCK1) (AA 1-377) antibodyNCK1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-NCK Adaptor Protein 1 (NCK1) (AA 53-333) antibodyNCK1 适用: 人 WB, IHC, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NCK Adaptor Protein 1 (NCK1) (AA 1-377) antibodyNCK1 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-NCK Adaptor Protein 1 (NCK1) (Internal Region) antibodyNCK1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-NCK Adaptor Protein 1 (NCK1) antibodyNCK1 适用: 人, 小鼠 WB, ICC 宿主: 小鼠 Monoclonal EM-06 unconjugated
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- NCK1 (NCK Adaptor Protein 1 (NCK1))
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别名
- NCK1
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背景
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Synonyms: SH2/SH3 adapter protein NCK1|Cytoplasmic protein NCK1|NCK adapter protein 1 (Nck-1)|SH2/SH3 adapter protein NCK-alpha|NCK1|NCK
Background: Adapter protein which associates with tyrosine-phosphorylated growth factor receptors, such as KDR and PDGFRB, or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in the DNA damage response, not in the detection of the damage by ATM/ATR, but for efficient activation of downstream effectors, such as that of CHEK2. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling. Modulates the activation of EIF2AK2/PKR by dsRNA. May play a role in cell adhesion and migration through interaction with ephrin receptors.
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分子量
- 43 kDa
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基因ID
- 4690
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UniProt
- P16333
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途径
- TCR Signaling, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
抗原
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