MX1 抗体
Quick Overview for MX1 抗体 (ABIN7116666)
抗原
See all MX1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- MX1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- Myxovirus resistance protein 1
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亚型
- IgG
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应用备注
- WB: 1:500-1:1000, IP: 1:500-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- MX1 (Myxovirus Resistance Protein 1 (MX1))
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别名
- MX1
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背景
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Synonyms: Interferon-induced GTP-binding protein Mx1|Interferon-induced protein p78 (IFI-78K)|Interferon-regulated resistance GTP-binding protein MxA|Myxoma resistance protein 1|Myxovirus resistance protein 1|Interferon-induced GTP-binding protein Mx1, N-terminally processed|MX1
Background: Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus(THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus(LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress. Inhibits influenza A virus(IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles. Enhances ER stress-mediated cell death after influenza virus infection. May regulate the calcium channel activity of TRPCs.
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分子量
- 76 kDa
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基因ID
- 4599
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UniProt
- P20591
抗原
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