Myosin VIIA 抗体
Quick Overview for Myosin VIIA 抗体 (ABIN7116628)
抗原
See all Myosin VIIA (MYO7A) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- MYO7A antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- myosin VIIA
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亚型
- IgG
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anti-Myosin VIIA (MYO7A) antibody
MYO7A 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myosin VIIA (MYO7A) (AA 838-968) antibodyMYO7A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Myosin VIIA (MYO7A) (AA 851-950) antibodyMYO7A 适用: 人, 小鼠 ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Myosin VIIA (MYO7A) (AA 2118-2213) antibodyMYO7A 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1D3 unconjugated
anti-Myosin VIIA (MYO7A) (AA 2118-2213) antibodyMYO7A 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Myosin VIIA (MYO7A) (AA 850-1150) antibodyMYO7A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- Myosin VIIA (MYO7A)
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别名
- MYO7A
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背景
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Synonyms: Unconventional myosin-VIIa|MYO7A|USH1B
Background: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. In the retina, plays an important role in the renewal of the outer photoreceptor disks. Plays an important role in the distribution and migration of retinal pigment epithelial(RPE) melanosomes and phagosomes, and in the regulation of opsin transport in retinal photoreceptors. In the inner ear, plays an important role in differentiation, morphogenesis and organization of cochlear hair cell bundles. Involved in hair-cell vesicle trafficking of aminoglycosides, which are known to induce ototoxicity(By similarity). Motor protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.
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分子量
- 160-255 kDa
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基因ID
- 4647
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UniProt
- Q13402
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途径
- Sensory Perception of Sound
抗原
-
