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Myosin VIIA 抗体

This anti-Myosin VIIA antibody is a 兔 多克隆 antibody detecting Myosin VIIA in ELISA, WB 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7116628
发货至: 中国

Quick Overview for Myosin VIIA 抗体 (ABIN7116628)

抗原

See all Myosin VIIA (MYO7A) 抗体
Myosin VIIA (MYO7A)

适用

  • 41
  • 26
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 40
  • 2

克隆类型

  • 38
  • 4
多克隆

标记

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  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This Myosin VIIA antibody is un-conjugated

应用范围

  • 17
  • 13
  • 13
  • 10
  • 8
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
ELISA, Western Blotting (WB), Immunofluorescence (IF)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    myosin VIIA

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000, IF: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    Myosin VIIA (MYO7A)

    别名

    MYO7A

    背景

    Synonyms:USH1B Background:Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. In the retina, plays an important role in the renewal of the outer photoreceptor disks. Plays an important role in the distribution and migration of retinal pigment epithelial(RPE) melanosomes and phagosomes, and in the regulation of opsin transport in retinal photoreceptors. In the inner ear, plays an important role in differentiation, morphogenesis and organization of cochlear hair cell bundles. Involved in hair-cell vesicle trafficking of aminoglycosides, which are known to induce ototoxicity(By similarity). Motor protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.

    分子量

    160-255kd

    基因ID

    4647

    UniProt

    Q13402

    途径

    Sensory Perception of Sound
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