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MLXIP 抗体

This anti-MLXIP antibody is a 兔 多克隆 antibody detecting MLXIP in ELISA, WB, IHC 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7116474
发货至: 中国

Quick Overview for MLXIP 抗体 (ABIN7116474)

抗原

See all MLXIP 抗体
MLXIP (MLX Interacting Protein (MLXIP))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This MLXIP antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    MLX interacting protein

    亚型

    IgG
  • 应用备注

    WB: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:10-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    MLXIP (MLX Interacting Protein (MLXIP))

    别名

    MLXIP

    背景

    Synonyms:BHLHE36, KIAA0867, MIR, MONDOA Background:Mlx-interacting protein(MLXIP), after forming heterodimers with MLX, can bind to and then activate transcription from CACGTG E boxes. The N terminus of MLXIP acts as a CRM1-dependent nuclear export signal and contribute to the cytoplasmic localization of the complex, and as a binding site for 13 protein. the C terminus contains a cytoplasmic localization signal and mediates protein-protein interaction of MONDOA and MLX. The complex play a role in transcriptional activation of glycolytic target genes and glucose-responsive gene regulation. This antibody could recognize isoform1(~110kd) and isoform3(~69kd) of MLXIP. A specific MLXIP of approximately 130 kDa was detected. It demonstrates that MLXIP associated specifically with Mlx in the cytoplasm (PMID: 11073985).

    分子量

    130 kDa

    基因ID

    22877

    UniProt

    Q9HAP2
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