MLXIP 抗体
Quick Overview for MLXIP 抗体 (ABIN7116474)
抗原
See all MLXIP 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- MLXIP antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- MLX interacting protein
-
亚型
- IgG
-
-
-
-
应用备注
- WB: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:10-1:100
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- MLXIP (MLX Interacting Protein (MLXIP))
-
别名
- MLXIP
-
背景
-
Synonyms: MLX-interacting protein|Class E basic helix-loop-helix protein 36 (bHLHe36)|Transcriptional activator MondoA|MLXIP|BHLHE36|KIAA0867|MIR|MONDOA
Background: Mlx-interacting protein(MLXIP), after forming heterodimers with MLX, can bind to and then activate transcription from CACGTG E boxes. The N terminus of MLXIP acts as a CRM1-dependent nuclear export signal and contribute to the cytoplasmic localization of the complex, and as a binding site for 13 protein. the C terminus contains a cytoplasmic localization signal and mediates protein-protein interaction of MONDOA and MLX. The complex play a role in transcriptional activation of glycolytic target genes and glucose-responsive gene regulation. This antibody could recognize isoform1(~110kd) and isoform3(~69kd) of MLXIP. A specific MLXIP of approximately 130 kDa was detected. It demonstrates that MLXIP associated specifically with Mlx in the cytoplasm (PMID: 11073985).
-
分子量
- 130 kDa
-
基因ID
- 22877
-
UniProt
- Q9HAP2
抗原
-