MFN2 抗体
Our Local Distributor
北京 101111
Quick Overview for MFN2 抗体 (ABIN7116407)
抗原
See all MFN2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- MFN2 antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- mitofusin 2
-
亚型
- IgG
-
-
anti-Mitofusin 2 (MFN2) (AA 661-757) antibody
MFN2 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 4H8 unconjugated
anti-Mitofusin 2 (MFN2) (AA 1-120) antibodyMFN2 适用: 人, 小鼠, 大鼠, 兔 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 2 (MFN2) (AA 500-600) antibodyMFN2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 2 (MFN2) (AA 687-757) antibodyMFN2 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 2 (MFN2) (AA 447-476) antibodyMFN2 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 2 (MFN2) (N-Term) antibodyMFN2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 2 (MFN2) (AA 370-600) antibodyMFN2 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S153-5 unconjugated
anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (HRP)MFN2 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S153-5 HRP
anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (FITC)MFN2 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S153-5 FITC
anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (Biotin)MFN2 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S153-5 Biotin
-
-
应用备注
- IP: 1:200-1:1000, WB: 1:200-1:1000, IHC: 1:50-1:500
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- MFN2 (Mitofusin 2 (MFN2))
-
别名
- MFN2
-
背景
-
Synonyms: Mitofusin-2|Transmembrane GTPase MFN2|MFN2|CPRP1|KIAA0214
Background: Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN2 acts independently of the cytoskeleton. It therefore plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Overexpression induces the formation of mitochondrial networks. Plays an important role in the regulation of vascular smooth muscle cell proliferation. Involved in the clearance of damaged mitochondria via selective autophagy(mitophagy). Is required for PARK2 recruitment to dysfunctional mitochondria. Involved in the control of unfolded protein response(UPR) upon ER stress including activation of apoptosis and autophagy during ER stress. Acts as an upstream regulator of EIF2AK3 and suppresses EIF2AK3 activation under basal conditions.
-
分子量
- 86 kDa
-
基因ID
- 9927
-
UniProt
- O95140
-
途径
- Skeletal Muscle Fiber Development
抗原
-
