C20orf72 抗体
Quick Overview for C20orf72 抗体 (ABIN7116334)
抗原
适用
宿主
克隆类型
标记
应用范围
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原理
- MGME1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- chromosome 20 open reading frame 72
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亚型
- IgG
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anti-Mitochondrial Genome Maintenance Exonuclease 1 (MGME1) (AA 81-260) antibody
MGME1 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- C20orf72 (MGME1) (Mitochondrial Genome Maintenance Exonuclease 1 (MGME1))
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别名
- MGME1
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背景
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Synonyms: Mitochondrial genome maintenance exonuclease 1|MGME1|C20orf72|DDK1
Background: Metal-dependent single-stranded DNA(ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA(mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA-primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair. Specifically binds 5-hydroxymethylcytosine(5hmC)-containing DNA in stem cells.
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分子量
- 36-39 kDa
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基因ID
- 92667
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UniProt
- Q9BQP7
抗原
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