MAP4K6 抗体 (AA 1-304)
Quick Overview for MAP4K6 抗体 (AA 1-304) (ABIN7116324)
抗原
See all MAP4K6 (MINK1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-304
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原理
- MINK1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 1-304aa
Immunogen: misshapen-like kinase 1(zebrafish)
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亚型
- IgG
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anti-Misshapen-Like Kinase 1 (MINK1) (Internal Region) antibody
MINK1 适用: 人, 小鼠, 大鼠, Cow, Pig, 马, Bat, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Misshapen-Like Kinase 1 (MINK1) (Internal Region) antibodyMINK1 适用: 人, 小鼠, 大鼠, Pig, 马, Bat, 猴, Hamster ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Misshapen-Like Kinase 1 (MINK1) (Internal Region) antibodyMINK1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Misshapen-Like Kinase 1 (MINK1) (Internal Region) antibodyMINK1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Misshapen-Like Kinase 1 (MINK1) (AA 755-804) antibodyMINK1 适用: 人, 小鼠, 大鼠, Cow, Pig, 马, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Misshapen-Like Kinase 1 (MINK1) (C-Term) antibodyMINK1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Misshapen-Like Kinase 1 (MINK1) (Middle Region) antibodyMINK1 适用: 人, 小鼠, 大鼠, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Misshapen-Like Kinase 1 (MINK1) (Internal Region) antibodyMINK1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- MAP4K6 (MINK1) (Misshapen-Like Kinase 1 (MINK1))
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别名
- MINK1
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背景
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Synonyms: Misshapen-like kinase 1|GCK family kinase MiNK|MAPK/ERK kinase kinase kinase 6 (MEK kinase kinase 6, MEKKK 6)|Misshapen/NIK-related kinase|Mitogen-activated protein kinase kinase kinase kinase 6|MINK1|B55|MAP4K6|MINK|YSK2|ZC3
Background: Serine/threonine kinase which acts as a negative regulator of Ras-related Rap2-mediated signal transduction to control neuronal structure and AMPA receptor trafficking. Required for normal synaptic density, dendrite complexity, as well as surface AMPA receptor expression in hippocampal neurons. Can activate the JNK and MAPK14/p38 pathways and mediates stimulation of the stress-activated protein kinase MAPK14/p38 MAPK downstream of the Raf/ERK pathway. Phosphorylates: TANC1 upon stimulation by RAP2A, MBP and SMAD1. Has an essential function in negative selection of thymocytes, perhaps by coupling NCK1 to activation of JNK1. Isoform 4 can activate the JNK pathway. Involved in the regulation of actin cytoskeleton reorganization, cell-matrix adhesion, cell-cell adhesion and cell migration.
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分子量
- 150 kDa
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基因ID
- 50488
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UniProt
- Q8N4C8
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途径
- Synaptic Membrane
抗原
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