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MCM8 抗体

MCM8 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7116318
发货至: 中国
  • 抗原 See all MCM8 抗体
    MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))
    适用
    • 32
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 31
    • 1
    克隆类型
    • 31
    • 1
    多克隆
    标记
    • 17
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MCM8 antibody is un-conjugated
    应用范围
    • 21
    • 17
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    minichromosome maintenance complex component 8
    亚型
    IgG
    Top Product
    Discover our top product MCM8 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))
    别名
    MCM8 (MCM8 产品)
    背景
    Synonyms:C20orf154 Background:Component of the MCM8-MCM9 complex, a complex involved in homologous recombination repair following DNA interstrand cross-links and plays a key role during gametogenesis. The MCM8-MCM9 complex probably acts as a hexameric helicase downstream of the Fanconi anemia proteins BRCA2 and RAD51 and is required to process aberrant forks into homologous recombination substrates and to orchestrate homologous recombination with resection, fork stabilization and fork restart. May also play a non-essential for DNA replication: may be involved in the activation of the prereplicative complex(pre-RC) during G(1) phase by recruiting CDC6 to the origin recognition complex(ORC). Binds chromatin throughout the cell cycle.
    分子量
    95 kDa
    基因ID
    84515
    UniProt
    Q9UJA3
    途径
    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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