MACF1 抗体
Quick Overview for MACF1 抗体 (ABIN7116291)
抗原
See all MACF1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- MACF1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- microtubule-actin crosslinking factor 1
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亚型
- IgG
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anti-Microtubule-Actin Crosslinking Factor 1 (MACF1) (AA 1-95) antibody
MACF1 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1G9 unconjugated
anti-Microtubule-Actin Crosslinking Factor 1 (MACF1) (AA 1-95) antibodyMACF1 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Microtubule-Actin Crosslinking Factor 1 (MACF1) (AA 1936-2150) antibodyMACF1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- MACF1 (Microtubule-Actin Crosslinking Factor 1 (MACF1))
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别名
- MACF1
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背景
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Synonyms: Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5|620 kDa actin-binding protein (ABP620)|Actin cross-linking family protein 7|Macrophin-1|Trabeculin-alpha|MACF1|ABP620|ACF7|KIAA0465|KIAA0754|KIAA1251
Background: Isoform 2 is a F-actin-binding protein which may play a role in cross-linking actin to other cytoskeletal proteins and also binds to microtubules. Plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. Acts as a positive regulator of Wnt receptor signaling pathway and is involved in the translocation of AXIN1 and its associated complex(composed of APC, CTNNB1 and GSK3B) from the cytoplasm to the cell membrane. Has actin-regulated ATPase activity and is essential for controlling focal adhesions(FAs) assembly and dynamics. May play role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with GOLGA4. Plays a key role in wound healing and epidermal cell migration. Required for efficient upward migration of bulge cells in response to wounding and this function is primarily rooted in its ability to coordinate MT dynamics and polarize hair follicle stem cells(By similarity).
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分子量
- 83 kDa
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基因ID
- 23499
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UniProt
- Q9UPN3
抗原
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