MITF 抗体
Quick Overview for MITF 抗体 (ABIN7116282)
抗原
See all MITF 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- MITF antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- microphthalmia-associated transcription factor
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IP: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- MITF (Microphthalmia-Associated Transcription Factor (MITF))
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别名
- MITF
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背景
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Synonyms: Microphthalmia-associated transcription factor|Class E basic helix-loop-helix protein 32 (bHLHe32)|MITF|BHLHE32
Background: Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences(E-boxes)(5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase(TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase(TYR) and tyrosinase-related protein 1(TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.
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分子量
- 60-65 kDa
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基因ID
- 4286
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UniProt
- O75030
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途径
- Chromatin Binding
抗原
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