MTF2 抗体
Quick Overview for MTF2 抗体 (ABIN7116220)
抗原
See all MTF2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- MTF2 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- metal response element binding transcription factor 2
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亚型
- IgG
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anti-Metal Response Element Binding Transcription Factor 2 (MTF2) (AA 1-190) antibody
MTF2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Metal Response Element Binding Transcription Factor 2 (MTF2) (AA 289-317) antibodyMTF2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal RB38307 unconjugated
anti-Metal Response Element Binding Transcription Factor 2 (MTF2) (Middle Region) antibodyMTF2 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Metal Response Element Binding Transcription Factor 2 (MTF2) (Middle Region) antibodyMTF2 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 斑马鱼, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Metal Response Element Binding Transcription Factor 2 (MTF2) antibodyMTF2 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Metal Response Element Binding Transcription Factor 2 (MTF2) antibodyMTF2 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Metal Response Element Binding Transcription Factor 2 (MTF2) (AA 1-536) antibodyMTF2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Metal Response Element Binding Transcription Factor 2 (MTF2) (AA 1-536) antibodyMTF2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Metal Response Element Binding Transcription Factor 2 (MTF2) (AA 359-408) antibodyMTF2 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Metal Response Element Binding Transcription Factor 2 (MTF2) (AA 26-75) antibodyMTF2 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 斑马鱼, Pig, 豚鼠, Bat, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:1000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- MTF2 (Metal Response Element Binding Transcription Factor 2 (MTF2))
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别名
- MTF2
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背景
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Synonyms: Metal-response element-binding transcription factor 2|Metal regulatory transcription factor 2|Metal-response element DNA-binding protein M96|Polycomb-like protein 2 (hPCl2)|MTF2|PCL2
Background: Polycomb group(PcG) that specifically binds histone H3 trimethylated at 'Lys-36'(H3K36me3) and recruits the PRC2 complex. Acts by binding to H3K36me3, a mark for transcriptional activation, and recruiting the PRC2 complex, leading to enhance PRC2 H3K27me3 methylation activity. Regulates the transcriptional networks during embryonic stem cell self-renewal and differentiation. Promotes recruitment of the PRC2 complex to the inactive X chromosome in differentiating XX ES cells and PRC2 recruitment to target genes in undifferentiated ES cells. Required to repress Hox genes by enhancing H3K27me3 methylation of the PRC2 complex. In some conditions may act as an inhibitor of PRC2 activity: able to activate the CDKN2A gene and promote cellular senescence by suppressing the catalytic activity of the PRC2 complex locally. Binds to the metal-regulating-element(MRE) of MT1A gene promoter(By similarity).
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分子量
- 60-61 kDa
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基因ID
- 22823
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UniProt
- Q9Y483
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途径
- Stem Cell Maintenance
抗原
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