MARCHF8 抗体
Quick Overview for MARCHF8 抗体 (ABIN7116199)
抗原
适用
宿主
克隆类型
标记
应用范围
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原理
- MARCHF8 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- membrane-associated ring finger(C3HC4) 8
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亚型
- IgG
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应用备注
- WB: 1:500-1:1000, IP: 1:200-1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- MARCHF8
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背景
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Synonyms: E3 ubiquitin-protein ligase MARCHF8|Cellular modulator of immune recognition (c-MIR)|Membrane-associated RING finger protein 8|Membrane-associated RING-CH protein VIII (MARCH-VIII)|RING finger protein 178|RING-type E3 ubiquitin transferase MARCHF8|MARCHF8|MARCH8|MIR|RNF178
Background: E3 ubiquitin-protein ligase that mediates ubiquitination of CD86 and MHC class II proteins, such as HLA-DR alpha and beta, and promotes their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. May also promote ubiquitination and endocytosis of TFRC and FAS.
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分子量
- 33 kDa
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基因ID
- 220972
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UniProt
- Q5T0T0
抗原
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