NG2 抗体
Quick Overview for NG2 抗体 (ABIN7116175)
抗原
See all NG2 (MCSP) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- CSPG4 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- chondroitin sulfate proteoglycan 4
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亚型
- IgG
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应用备注
- WB: 1:500-1:5000, IHC: 1:50-1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))
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别名
- CSPG4
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背景
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Synonyms: Chondroitin sulfate proteoglycan 4|Chondroitin sulfate proteoglycan NG2|Melanoma chondroitin sulfate proteoglycan|Melanoma-associated chondroitin sulfate proteoglycan|CSPG4|MCSP
Background: CSPG4, also named as HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16 and NG2, is a proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. CSPG4 may inhibit neurite outgrowth and growth cone collapse during axon regeneration. It is cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. CSPG4 may regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties. It modulates the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin.
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分子量
- 240-250 kDa
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基因ID
- 1464
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UniProt
- Q6UVK1
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途径
- Glycosaminoglycan Metabolic Process
抗原
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