MAGED1 抗体
Quick Overview for MAGED1 抗体 (ABIN7116167)
抗原
See all MAGED1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- MAGED1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- melanoma antigen family D, 1
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))
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别名
- MAGED1
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背景
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Synonyms: Melanoma-associated antigen D1|MAGE tumor antigen CCF|MAGE-D1 antigen|Neurotrophin receptor-interacting MAGE homolog|MAGED1|NRAGE
Background: Involved in the apoptotic response after nerve growth factor(NGF) binding in neuronal cells. Inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme(E2) at the E3:substrate complex. Plays a role in the circadian rythm regulation. May act as RORA co-regulator, modulating the expression of core clock genes such as ARNTL/BMAL1 and NFIL3, induced, or NR1D1, repressed.
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分子量
- 100 kDa
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基因ID
- 9500
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UniProt
- Q9Y5V3
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途径
- Neurotrophin Signaling Pathway
抗原
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