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MAGEA3 抗体

This anti-MAGEA3 antibody is a 小鼠 单克隆 antibody detecting MAGEA3 in WB, ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7116156
发货至: 中国

Quick Overview for MAGEA3 抗体 (ABIN7116156)

抗原

See all MAGEA3 抗体
MAGEA3 (Melanoma Antigen Family A, 3 (MAGEA3))

适用

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宿主

  • 30
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小鼠

克隆类型

  • 31
  • 10
  • 1
单克隆

标记

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This MAGEA3 antibody is un-conjugated

应用范围

  • 30
  • 19
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

克隆位点

4E9
  • 纯化方法

    Protein A+G purification

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    melanoma antigen family A, 3

    亚型

    IgG2a
  • 应用备注

    WB: 1:500-1:2000, IHC: 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    MAGEA3 (Melanoma Antigen Family A, 3 (MAGEA3))

    别名

    MAGEA3

    背景

    Synonyms:Antigen MZ2 D, Cancer/testis antigen 1.3, CT1.3, HIP8, HYPD, MAGE 3 antigen, MAGE3, MAGEA3, MAGE-A3, MAGEA6, melanoma antigen family A, 3, Melanoma associated antigen 3 Background:Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme(E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.

    分子量

    35-55 kDa

    基因ID

    4102

    UniProt

    P43357
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