MAGEA3 抗体
Quick Overview for MAGEA3 抗体 (ABIN7116156)
抗原
See all MAGEA3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- MAGEA3 antibody
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纯化方法
- Protein A+G purification
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- melanoma antigen family A, 3
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亚型
- IgG2a
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应用备注
- WB: 1:500-1:2000, IHC: 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- MAGEA3 (Melanoma Antigen Family A, 3 (MAGEA3))
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别名
- MAGEA3
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背景
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Synonyms: Melanoma-associated antigen 3|Antigen MZ2-D|Cancer/testis antigen 1.3 (CT1.3)|MAGE-3 antigen|MAGEA3|MAGE3
Background: Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme(E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
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分子量
- 35-55 kDa
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基因ID
- 4102
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UniProt
- P43357
抗原
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