MED12L 抗体

Synonyms: Mediator of RNA polymerase II transcription subunit 12-like protein|Mediator complex subunit 12-like protein|Thyroid hormone receptor-associated-like protein|Trinucleotide repeat-containing gene 11 protein-like|MED12L|KIAA1635|TNRC11L|TRALP|TRALPUSH

Background: May be a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors(By similarity).