KDM5C 抗体
Quick Overview for KDM5C 抗体 (ABIN7115965)
抗原
See all KDM5C 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- KDM5C antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- lysine(K)-specific demethylase 5C
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- KDM5C (Lysine (K)-Specific Demethylase 5C (KDM5C))
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别名
- KDM5C
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背景
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Synonyms: Lysine-specific demethylase 5C|Histone demethylase JARID1C|Jumonji/ARID domain-containing protein 1C|Protein SmcX|Protein Xe169|[histone H3]-trimethyl-L-lysine(4) demethylase 5C|KDM5C|DXS1272E|JARID1C|SMCX|XE169
Background: Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements. Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2(By similarity).
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分子量
- 171-180 kDa
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基因ID
- 8242
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UniProt
- P41229
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途径
- Warburg Effect
抗原
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