LONP1 抗体
Quick Overview for LONP1 抗体 (ABIN7115913)
抗原
See all LONP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- LONP1 antibody
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纯化方法
- Protein A+G purification
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- lon peptidase 1, mitochondrial
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亚型
- IgG2a
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应用备注
- WB: 1:500-1:10000, IHC: 1:400-1:1600, IF: 1:10-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- LONP1 (Lon Peptidase 1, Mitochondrial (LONP1))
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别名
- LONP1
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背景
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Synonyms: Lon protease homolog, mitochondrial|LONHs|Lon protease-like protein (LONP)|Mitochondrial ATP-dependent protease Lon|Serine protease 15|LONP1|PRSS15
Background: ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand-specific manner. May regulate mitochondrial DNA replication and/or gene expression using site-specific, single-stranded DNA binding to target the degradation of regulatory proteins binding to adjacent sites in mitochondrial promoters. Endogenous substrates include mitochondrial steroidogenic acute regulatory(StAR) protein.
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分子量
- 100 kDa
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基因ID
- 9361
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UniProt
- P36776
抗原
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