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LIN7B 抗体

LIN7B 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7115885
发货至: 中国
  • 抗原 See all LIN7B 抗体
    LIN7B (Lin-7 Homolog B (LIN7B))
    适用
    人, 小鼠, 大鼠
    宿主
    • 16
    • 1
    克隆类型
    • 17
    多克隆
    标记
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    This LIN7B antibody is un-conjugated
    应用范围
    Western Blotting (WB), ELISA
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    lin-7 homolog B(C. elegans)
    亚型
    IgG
    Top Product
    Discover our top product LIN7B Primary Antibody
  • 应用备注
    WB: 1:500-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    LIN7B (Lin-7 Homolog B (LIN7B))
    别名
    LIN7B (LIN7B 产品)
    别名
    LIN7B antibody, LIN-7B antibody, MALS-2 antibody, MALS2 antibody, VELI2 antibody, Veli2 antibody, Veli1a antibody, lin-7 homolog B, crumbs cell polarity complex component antibody, lin-7 homolog B (C. elegans) antibody, LIN7B antibody, Lin7b antibody
    背景
    Synonyms:MALS2, VELI2 Background:Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7(LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B(subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter(SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells. May increase the amplitude of ASIC3 acid-evoked currents by stabilizing the channel at the cell surface(By similarity).
    分子量
    23kd
    基因ID
    64130
    UniProt
    Q9HAP6
    途径
    Synaptic Membrane
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