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LIN7B 抗体

This anti-LIN7B antibody (ABIN7115885) is a Rabbit Polyclonal antibody detecting LIN7B in WB, ELISA. Suitable for Human, Mouse, Rat.
产品编号 ABIN7115885
发货至: 中国

Quick Overview for LIN7B 抗体 (ABIN7115885)

抗原

See all LIN7B 抗体
LIN7B (Lin-7 Homolog B (LIN7B))

适用

人, 小鼠, 大鼠

宿主

  • 11
  • 2
  • 1

克隆类型

  • 12
  • 2
多克隆

标记

  • 9
  • 1
  • 1
  • 1
  • 1
  • 1
This LIN7B antibody is un-conjugated

应用范围

  • 14
  • 9
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    lin-7 homolog B(C. elegans)

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    LIN7B (Lin-7 Homolog B (LIN7B))

    别名

    LIN7B

    背景

    Synonyms:MALS2, VELI2 Background:Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7(LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B(subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter(SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells. May increase the amplitude of ASIC3 acid-evoked currents by stabilizing the channel at the cell surface(By similarity).

    分子量

    23kd

    基因ID

    64130

    UniProt

    Q9HAP6

    途径

    Synaptic Membrane
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