LIN7A 抗体
Our Local Distributor
北京 101111
Quick Overview for LIN7A 抗体 (ABIN7115884)
抗原
See all LIN7A 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- LIN7A antibody
-
纯化方法
- Immunogen affinity purified
-
纯度
- ≥95 % as determined by SDS-PAGE
-
免疫原
- lin-7 homolog A(C. elegans)
-
亚型
- IgG
-
-
anti-Lin-7 Homolog A (LIN7A) (AA 1-233) antibody
LIN7A 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Lin-7 Homolog A (LIN7A) (AA 1-233) antibodyLIN7A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
-
-
应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- -20°C for 12 months
-
有效期
- 12 months
-
-
- LIN7A (Lin-7 Homolog A (LIN7A))
-
别名
- LIN7A
-
背景
-
Synonyms: Protein lin-7 homolog A (Lin-7A, hLin-7)|Mammalian lin-seven protein 1 (MALS-1)|Tax interaction protein 33 (TIP-33)|Vertebrate lin-7 homolog 1 (Veli-1)|LIN7A|MALS1|VELI1
Background: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7(LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B(subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter(SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.
-
分子量
- 28-30 kDa
-
基因ID
- 8825
-
UniProt
- O14910
-
途径
- Synaptic Membrane
抗原
-
