LARGE 抗体
Quick Overview for LARGE 抗体 (ABIN7115863)
抗原
See all LARGE 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- like-glycosyltransferase
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亚型
- IgG
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anti-Like-Glycosyltransferase (LARGE) (AA 25-178) antibody
LARGE 适用: 人 WB, IP, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Like-Glycosyltransferase (LARGE) (AA 365-398) antibodyLARGE 适用: 人 WB 宿主: 兔 Polyclonal RB55257 unconjugated
anti-Like-Glycosyltransferase (LARGE) (AA 421-433) antibodyVerified LARGE 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Like-Glycosyltransferase (LARGE) (AA 683-732) antibodyLARGE 适用: 人, 小鼠, Cow, 犬, 豚鼠, 马, 兔, 大鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Like-Glycosyltransferase (LARGE) (Middle Region) antibodyLARGE 适用: 人, 小鼠, Cow, 犬, 豚鼠, 马, 兔, 大鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- LARGE (Like-Glycosyltransferase (LARGE))
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别名
- LARGE
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背景
- Synonyms:KIAA0609, LARGE1 Background:Bifunctional glycosyltransferase with both xylosyltransferase and beta-1,3-glucuronyltransferase activities involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide(N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan(DAG1)(PubMed:22223806). Phosphorylated O-mannosyl trisaccharid is required for binding laminin G-like domain-containing extracellular proteins with high affinity and plays a key role in skeletal muscle function and regeneration. LARGE elongates the glucuronyl-beta-1,4-xylose-beta disaccharide primer structure initiated by B3GNT1/B4GAT1 by adding repeating units [-3-Xylose-alpha-1,3-GlcA-beta-1-] to produce a heteropolysaccharide(PubMed:25279699).
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分子量
- 65-70 kDa
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基因ID
- 9215
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UniProt
- O95461
抗原
-
