LNX1 抗体
Quick Overview for LNX1 抗体 (ABIN7115860)
抗原
See all LNX1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- LNX1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- ligand of numb-protein X 1
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亚型
- IgG
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anti-Ligand of Numb-Protein X 1 (LNX1) (AA 19-118) antibody
LNX1 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 4E3 unconjugated
anti-Ligand of Numb-Protein X 1 (LNX1) (AA 133-259) antibodyLNX1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ligand of Numb-Protein X 1 (LNX1) (AA 19-118) antibodyLNX1 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ligand of Numb-Protein X 1 (LNX1) (AA 1-632) antibodyLNX1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ligand of Numb-Protein X 1 (LNX1) (AA 431-480) antibodyLNX1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 兔, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Ligand of Numb-Protein X 1 (LNX1) (C-Term) antibodyLNX1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- LNX1 (Ligand of Numb-Protein X 1 (LNX1))
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别名
- LNX1
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背景
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Synonyms: E3 ubiquitin-protein ligase LNX|Ligand of Numb-protein X 1|Numb-binding protein 1|PDZ domain-containing RING finger protein 2|RING-type E3 ubiquitin transferase LNX|LNX1|LNX|PDZRN2
Background: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65(By similarity). Isoform 2 provides an endocytic scaffold for IGSF5/JAM4.
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分子量
- 70 kDa
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基因ID
- 84708
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UniProt
- Q8TBB1
抗原
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