Leupaxin 抗体
Quick Overview for Leupaxin 抗体 (ABIN7115856)
抗原
See all Leupaxin (LPXN) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- LPXN antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- leupaxin
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- Leupaxin (LPXN)
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别名
- LPXN
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背景
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Synonyms: Leupaxin|LPXN|LDLP
Background: Transcriptional coactivator for androgen receptor(AR) and serum response factor(SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin-induced tyrosine phosphorylation of paxillin(PXN). May play a critical role as an adapter protein in the formation of the adhesion zone in osteoclasts. Negatively regulates B-cell antigen receptor(BCR) signaling.
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分子量
- 50-60 kDa
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基因ID
- 9404
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UniProt
- O60711
抗原
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