LGR6 抗体
Quick Overview for LGR6 抗体 (ABIN7115835)
抗原
See all LGR6 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- LGR6 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- leucine-rich repeat-containing G protein-coupled receptor 6
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亚型
- IgG
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应用备注
- WB: 1:200-1:1000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- LGR6 (Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 6 (LGR6))
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别名
- LGR6
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背景
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Synonyms: Leucine-rich repeat-containing G-protein coupled receptor 6|LGR6
Background: Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins(RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor.
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分子量
- 104 kDa
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基因ID
- 59352
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UniProt
- Q9HBX8
抗原
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