LRWD1 抗体
Quick Overview for LRWD1 抗体 (ABIN7115828)
抗原
See all LRWD1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- LRWD1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- leucine-rich repeats and WD repeat domain containing 1
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亚型
- IgG
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anti-Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1) (AA 1-30), (N-Term) antibody
LRWD1 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB29538 unconjugated
anti-Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1) (AA 4-33), (N-Term) antibodyLRWD1 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- LRWD1 (Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1))
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别名
- LRWD1
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背景
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Synonyms: Leucine-rich repeat and WD repeat-containing protein 1|Centromere protein 33 (CENP-33)|Origin recognition complex-associated protein (ORC-associated protein, ORCA)|LRWD1|CENP-33|ORCA
Background: Required for G1/S transition. Recruits and stabilizes the origin recognition complex(ORC) onto chromatin during G1 to establish pre-replication complex(preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K20me3 and H4K27me3 in a cooperative manner with DNA methylation. Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability.
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分子量
- 85 kDa
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基因ID
- 222229
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UniProt
- Q9UFC0
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途径
- Chromatin Binding
抗原
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