LRRC8D 抗体
This anti-LRRC8D antibody is a 兔 多克隆 antibody detecting LRRC8D in ELISA 和 WB. Suitable for 人, 小鼠 和 大鼠.
Quick Overview for LRRC8D 抗体 (ABIN7115814)
抗原
See all LRRC8D 抗体
LRRC8D
(Leucine Rich Repeat Containing 8 Family, Member D (LRRC8D))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This LRRC8D antibody is un-conjugated
应用范围
ELISA, Western Blotting (WB)
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- leucine rich repeat containing 8 family, member D
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亚型
- IgG
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anti-Leucine Rich Repeat Containing 8 Family, Member D (LRRC8D) (AA 1-143) antibody
LRRC8D 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 3H1-1C2 unconjugated
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应用备注
- WB: 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- LRRC8D (Leucine Rich Repeat Containing 8 Family, Member D (LRRC8D))
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别名
- LRRC8D
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背景
- Synonyms:LRRC5 Background:Non-essential component of the volume-regulated anion channel(VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. Channel activity requires LRRC8A plus at least one other family member(LRRC8B, LRRC8C, LRRC8D or LRRC8E), channel characteristics depend on the precise subunit composition(PubMed:24790029, PubMed:26824658). LRRC8A and LRRC8D are required for the uptake of the drug cisplatin(PubMed:26530471). Mediates the import of the antibiotic blasticidin-S into the cell(PubMed:24782309).
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分子量
- 98-120 kDa
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基因ID
- 55144
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UniProt
- Q7L1W4
抗原
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