LRSAM1 抗体
Quick Overview for LRSAM1 抗体 (ABIN7115802)
抗原
See all LRSAM1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- LRSAM1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- leucine rich repeat and sterile alpha motif containing 1
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- LRSAM1 (Leucine Rich Repeat and Sterile alpha Motif Containing 1 (LRSAM1))
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别名
- LRSAM1
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背景
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Synonyms: E3 ubiquitin-protein ligase LRSAM1|Leucine-rich repeat and sterile alpha motif-containing protein 1|RING-type E3 ubiquitin transferase LRSAM1|Tsg101-associated ligase (hTAL)|LRSAM1|TAL
Background: E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivate the ability of TSG101 to sort endocytic(EGF receptors) and exocytic(HIV-1 viral proteins) cargos(PubMed:15256501). Bacterial recognition protein that defends the cytoplasm from invasive pathogens(PubMed:23245322). Localizes to several intracellular bacterial pathogens and generates the bacteria-associated ubiquitin signal leading to autophagy-mediated intracellular bacteria degradation(xenophagy)(PubMed:23245322, PubMed:25484098).
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分子量
- 84 kDa
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基因ID
- 90678
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UniProt
- Q6UWE0
抗原
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