KLF10/TIEG1 抗体
Quick Overview for KLF10/TIEG1 抗体 (ABIN7115728)
抗原
See all KLF10/TIEG1 (KLF10) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- KLF10 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- Kruppel-like factor 10
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- KLF10/TIEG1 (KLF10) (Kruppel-Like Factor 10 (KLF10))
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别名
- KLF10
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背景
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Synonyms: Krueppel-like factor 10|EGR-alpha|Transforming growth factor-beta-inducible early growth response protein 1 (TGFB-inducible early growth response protein 1, TIEG-1)|KLF10|TIEG|TIEG1
Background: Transcriptional repressor which binds to the consensus sequence 5'-GGTGTG-3'. Plays a role in the regulation of the circadian clock, binds to the GC box sequence in the promoter of the core clock component ARTNL/BMAL1 and represses its transcriptional activity. Regulates the circadian expression of genes involved in lipogenesis, gluconeogenesis, and glycolysis in the liver. Represses the expression of PCK2, a rate-limiting step enzyme of gluconeogenesis(By similarity). May play a role in the cell cycle regulation.
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分子量
- 52 kDa
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基因ID
- 7071
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UniProt
- Q13118
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途径
- Stem Cell Maintenance
抗原
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