KLHL21 抗体
Quick Overview for KLHL21 抗体 (ABIN7115598)
抗原
See all KLHL21 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- KLHL21 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- kelch-like 21(Drosophila)
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- KLHL21 (Kelch-Like 21 (KLHL21))
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别名
- KLHL21
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背景
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Synonyms: Kelch-like protein 21|KLHL21|KIAA0469
Background: Substrate-specific adapter of a BCR(BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex(CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.
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分子量
- 67 kDa
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基因ID
- 9903
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UniProt
- Q9UJP4
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途径
- M Phase
抗原
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