KATNB1 抗体
Quick Overview for KATNB1 抗体 (ABIN7115579)
抗原
See all KATNB1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- KATNB1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- katanin p80(WD repeat containing) subunit B 1
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IP: 1:500-1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- KATNB1 (Katanin P80 (WD Repeat Containing) Subunit B 1 (KATNB1))
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别名
- KATNB1
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背景
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Synonyms: Katanin p80 WD40 repeat-containing subunit B1 (Katanin p80 subunit B1)|p80 katanin|KATNB1
Background: Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.
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分子量
- 72-80 kDa
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基因ID
- 10300
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UniProt
- Q9BVA0
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途径
- Microtubule Dynamics
抗原
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