KPNA1 抗体
Quick Overview for KPNA1 抗体 (ABIN7115572)
抗原
See all KPNA1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- KPNA1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- karyopherin alpha 1 (importin alpha 5)
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亚型
- IgG
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应用备注
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- KPNA1 (Karyopherin alpha 1 (Importin alpha 5) (KPNA1))
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别名
- KPNA1
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背景
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Synonyms: Importin subunit alpha-5|Karyopherin subunit alpha-1|Nucleoprotein interactor 1 (NPI-1)|RAG cohort protein 2|SRP1-beta|Importin subunit alpha-5, N-terminally processed|KPNA1|RCH2
Background: The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import. This protein interacts with the recombination activating gene 1 (RAG1) protein and is a putative substrate of the RAG1 ubiquitin ligase. Alternative splicing results in multiple transcript variants.
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分子量
- 66 kDa
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基因ID
- 3836
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UniProt
- P52294
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途径
- M Phase, Protein targeting to Nucleus
抗原
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