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IDH1 抗体 (AA 120-414)

This 小鼠 单克隆 anti-IDH1 antibody (Clone 1G10) specifically detects IDH1 in WB, IHC, ELISA 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN7115525
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for IDH1 抗体 (AA 120-414) (ABIN7115525)

抗原

See all IDH1 抗体
IDH1 (Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This IDH1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

克隆位点

1G10
  • 抗原表位

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    AA 120-414

    原理

    IDH1 antibody

    纯化方法

    Protein A+G purification

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    Immunogen sequence: 120-414aa

    Immunogen: isocitrate dehydrogenase 1(NADP+), soluble

    亚型

    IgG1
  • 应用备注

    WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:50-1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    IDH1 (Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1))

    别名

    IDH1

    背景

    Synonyms: Isocitrate dehydrogenase [NADP] cytoplasmic (IDH, IDH1)|Cytosolic NADP-isocitrate dehydrogenase|IDPc|NADP(+)-specific ICDH|Oxalosuccinate decarboxylase|IDH1|PICD

    Background: IDH1, also named as PICD and IDP, belongs to the isocitrate and isopropylmalate dehydrogenases family. It is a common feature of a major subset of primary human brain cancers. It can form a homodimer(PMID:15173171).IDH1 mutation is always heterozygotic and IDH1 functions as a dimer, theoretically there will be 25 % each wild type and mutant homo-dimers and 50 % hetero-dimers present in the tumor cells(PMID:21079649 ).

    分子量

    46 kDa

    基因ID

    3417

    UniProt

    O75874

    途径

    Warburg Effect
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