IDH1 抗体 (AA 120-414)
Quick Overview for IDH1 抗体 (AA 120-414) (ABIN7115525)
抗原
See all IDH1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 120-414
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原理
- IDH1 antibody
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纯化方法
- Protein A+G purification
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 120-414aa
Immunogen: isocitrate dehydrogenase 1(NADP+), soluble
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亚型
- IgG1
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应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:50-1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- IDH1 (Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1))
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别名
- IDH1
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背景
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Synonyms: Isocitrate dehydrogenase [NADP] cytoplasmic (IDH, IDH1)|Cytosolic NADP-isocitrate dehydrogenase|IDPc|NADP(+)-specific ICDH|Oxalosuccinate decarboxylase|IDH1|PICD
Background: IDH1, also named as PICD and IDP, belongs to the isocitrate and isopropylmalate dehydrogenases family. It is a common feature of a major subset of primary human brain cancers. It can form a homodimer(PMID:15173171).IDH1 mutation is always heterozygotic and IDH1 functions as a dimer, theoretically there will be 25 % each wild type and mutant homo-dimers and 50 % hetero-dimers present in the tumor cells(PMID:21079649 ).
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分子量
- 46 kDa
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基因ID
- 3417
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UniProt
- O75874
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途径
- Warburg Effect
抗原
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