IQCB1 抗体
Quick Overview for IQCB1 抗体 (ABIN7115509)
抗原
See all IQCB1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- IQCB1 antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- IQ motif containing B1
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亚型
- IgG
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应用备注
- IF: 1:10-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- IQCB1 (IQ Motif Containing B1 (IQCB1))
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别名
- IQCB1
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背景
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Synonyms: IQ calmodulin-binding motif-containing protein 1|Nephrocystin-5|p53 and DNA damage-regulated IQ motif protein (PIQ)|IQCB1|KIAA0036|NPHP5
Background: IQCB1, also known as NPHP5, is a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. It has a central coiled-coil region and two calmodulin-binding IQ domains. Localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells, IQCB1 is thought to play a role in ciliary function. Mutations in this gene result in Senior-Loken syndrome type 5, a juvenile disorder characterized by defects in the waste filtering system of the kidney, as well as retinal degradation.
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UniProt
- Q15051
抗原
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