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IQCB1 抗体

This anti-IQCB1 antibody is a 兔 多克隆 antibody detecting IQCB1 in ELISA 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7115509
发货至: 中国
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北京 101111
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IQCB1 抗体 (ABIN7115509)

抗原

See all IQCB1 抗体
IQCB1 (IQ Motif Containing B1 (IQCB1))

适用

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人, 小鼠, 大鼠

宿主

  • 28
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克隆类型

  • 31
多克隆

标记

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This IQCB1 antibody is un-conjugated

应用范围

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ELISA, Immunofluorescence (IF)
  • 原理

    IQCB1 antibody

    纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    IQ motif containing B1

    亚型

    IgG
  • 应用备注

    IF: 1:10-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    IQCB1 (IQ Motif Containing B1 (IQCB1))

    别名

    IQCB1

    背景

    Synonyms: IQ calmodulin-binding motif-containing protein 1|Nephrocystin-5|p53 and DNA damage-regulated IQ motif protein (PIQ)|IQCB1|KIAA0036|NPHP5

    Background: IQCB1, also known as NPHP5, is a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. It has a central coiled-coil region and two calmodulin-binding IQ domains. Localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells, IQCB1 is thought to play a role in ciliary function. Mutations in this gene result in Senior-Loken syndrome type 5, a juvenile disorder characterized by defects in the waste filtering system of the kidney, as well as retinal degradation.

    UniProt

    Q15051
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