IL-33 抗体 (AA 1-270)
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北京 101111
Quick Overview for IL-33 抗体 (AA 1-270) (ABIN7115461)
抗原
See all IL-33 (IL33) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-270
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原理
- IL33 antibody
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纯化方法
- Protein A+G purification
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
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Immunogen sequence: 1-270aa
Immunogen: interleukin 33
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亚型
- IgG1
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anti-Interleukin 33 (IL33) (AA 112-270) antibody
IL33 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C11 unconjugated
anti-Interleukin 33 (IL33) antibodyIL33 适用: 人 WB, ELISA, IHC, IP, Func 宿主: 小鼠 Monoclonal IL33305B unconjugated
anti-Interleukin 33 (IL33) (AA 112-270) antibodyIL33 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C19 unconjugated
anti-Interleukin 33 (IL33) (AA 110-261) antibodyIL33 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 2# unconjugated
anti-Interleukin 33 (IL33) (AA 185-264) antibodyIL33 适用: 小鼠, 大鼠 ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 33 (IL33) antibodyIL33 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 33 (IL33) (AA 171-269) antibodyIL33 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D8 unconjugated
anti-Interleukin 33 (IL33) (AA 102-264) antibodyIL33 适用: 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 33 (IL33) antibodyIL33 适用: 人 WB, IHC (p), EIA, Func 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 33 (IL33) antibody (Biotin)IL33 适用: 人 WB, EIA 宿主: 兔 Polyclonal Biotin
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应用备注
- WB: 1:500-1:2000, IHC: 1:50-1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- IL-33 (IL33) (Interleukin 33 (IL33))
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别名
- IL33
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背景
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Synonyms: Interleukin-33 (IL-33)|Interleukin-1 family member 11 (IL-1F11)|Nuclear factor from high endothelial venules (NF-HEV)|Interleukin-33 (95-270)|Interleukin-33 (99-270)|Interleukin-33 (109-270)|IL33|C9orf26|IL1F11|NFHEV
Background: Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells(PubMed:16286016). Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an "alarmin", that amplifies immune responses during tissue injury(PubMed:17853410, PubMed:18836528). In quiescent endothelia the uncleaved form is constitutively and abundantly expressed, and acts as a chromatin-associated nuclear factor with transcriptional repressor properties, it may sequester nuclear NF-kappaB/RELA, lowering expression of its targets(PubMed:21734074). This form is rapidely lost upon angiogenic or proinflammatory activation(PubMed:18787100).
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分子量
- 35 kDa
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基因ID
- 90865
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UniProt
- O95760
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途径
- Production of Molecular Mediator of Immune Response
抗原
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